Authorship contributions
CD and EMA equally contributed to this work and are senior first authors. EMB, DTT, and HB equally contributed to this work and are co-senior authors. CD, EA, SEH, LV, KOM, JC, SH, EB, HB, and DTT designed the study, analyzed data, and wrote the manuscript; KC, ML, AMB, JCF, TJK, AROJ, KES, DF, DASP, MRT, DZ, MM, JHL, PY contributed to study design, analyzed data, and helped write the manuscript. EMA, MEW, SG, EC, MJB, CPA performed experiments, provided data, and edited manuscript. CD, JC, and KOM enrolled subjects. PY, DSP and DF also provided specimens. All authors contributed intellectually and reviewed and revised the manuscript.