Increasing trend of AAI prescription, especially among adult patients admitted for anaphylaxis
There was an overall increasing rate of AAI prescription for patients admitted for anaphylaxis during the study period. The AAI prescription rates among adult and pediatric patients with anaphylaxis are displayed longitudinally in Figure 2. Patients admitted for anaphylaxis in the year 2019 were significantly more likely to be prescribed an AAI compared to those admitted in 2009 (27.9% vs. 5.1%; OR=7.263, 95% CI=3.436-15.352; P <0.001). This difference was more marked in subgroup analysis of adult patients (16.2% vs. 0.8%; OR=25.180, 95% CI=3.427-185.020; P <0.001), but also held true for pediatric patients (64.0% vs. 25.9%; OR=5.069, 95% CI=1.928-13.329; P =0.001) between 2009 and 2019 .