There are three transmission elements of infectious diseases : source of infection, route of transmission and susceptible population. The maternal immune system of pregnant women is in a dilemma that it need to establish immunologic tolerance to the allogeneic fetus, while to defend the bodies from the invasion of pathogenic microorganisms. The maternal immunological states keep being in flux through the pregnant progress. Pregnancy drives women into a partial immune deficiency state[3]. It takes for granted that pregnant women own more possibility of infection on account of the COVID-19.Whereas some latest Chinese researches[1, 4, 5]drew the conclusion that pregnant women presented the equal opportunity of COVID-19 infection, compared with non-pregnant patients. This consequence shocks the common sense of the public, but still it may come to light if more cases are analyzed and geographic limitation is ruled out. Several evidences could prove the infection insurability between mothers and fetuses. We must keep vigilant to its potential risks. Researches prove that infection could activate the immune system and rise the level of some immune factors such as TNF-α and IL-17a, which could lead to brain development abnormalities, preterm labor, even fetal loss[6, 7].And fever as the most common and initial symptom of COVID-19 infection could be associated with increased attention-deficit/hyperactivity disorder in the offspring[3].