Procedure:
In this cross-sectional study, 88 children aged 0 to 18 years old with primary brain tumors were investigated. Data was extracted from patients’ medical records. 38 patients received Irinotecan treatment from the beginning (B) or after relapse (AB). At study termination, the response rate to the treatment as well as the Overall Survival (OS) and 6 months Progression Free Survival (6-mo-PFS) were estimated using Kaplan-Meier survival analysis and PFS estimation.