3.1 The profile of clinical data in each group
A total of 124 patients were enrolled and randomly divided into the ITD
group and the ITL group. The ITD group was further randomly divided into
the ITD1 (2mg/ml) and ITD2 (5mg/ml) groups. All the patients (174 ears)
with Méniere’s disease (59 men, 65 women; age range: 21 to 81 years old
)were treated with IT. The time between development of otologic
complaints and ITD treatment ranged from 6 months to 5 years and 2
months. Prior to the administration of IT, all patients had been treated
with other medications. All 124 had been treated with courses (often
multiple) of oral medicine. The comparison of the general clinical index
of each group before treatment (table 1 and table 2) showed no
statistically significant difference (P > 0.05), indicating
that the two groups had good equilibrium and were comparable.