Results are presented as mean ± SD with a 95% Confidence Interval. HS,Hypertonic saline; BMI, body mass index;FEV1, Forced Expiratory Volume in one second;FVC, Forced Vital Capacity; PEFR, Peak Expiratory Flow Rate;bpm,beats per minute
Primary outcome measure of this trial was the improvement of FEV1 after the intervention with Hypertonic Saline nebulization prior to chest physiotherapy. The mean FEV 1 improvement of children receiving HS was higher than those receiving conventional therapy, where the difference was statistically significant at both phases of the study as shown in table 2 and figure 2.
TABLE 2: Clinical and Spirometric improvement of dynamic lung volumes in the two groups during phase I and II