Pre-Conception
Prior to conception, pre-pregnancy counselling, risk stratification and
classification should guide management5,38. Ideally,
surgical intervention prior to conception in at-risk women is indicated
for certain thresholds. 45mm ascending aorta diameter in MFS, FTAAD or
SMAD3 mutation recommends repair prior to pregnancy; this is also the
case of Loeys-Dietz (40 – 45mm), BAV (50mm), TS (27mm, ASI) and others
(50mm)29.