Results
The mean (SD) age of study population was 58 (12.3). Of our patients,
2176 (65.8%) were male and 1133 (34.2%) were female. Radical and
partial nephrectomies were performed in 2099 (63.4%) and 1210 (36.6%)
patients, respectively. CT and MRI were performed in 2510 (75.8%) and
799 (24.2%) patients, respectively. The demographic and surgical data
of the patients are given in Table 1. There was a substantial
concordance between radiological and pathological staging (ะบ=0.52,
p<0.001) (Table 2). Sensitivity, specificity, negative and
positive predictive values and accuracy rates of radiologic staging for
pathologic stage are shown in table 3. The sensitivity in stage III was
lower than the other stages (p<0.05). Sub-analysis of stage
IIIa cases revealed that, for perirenal fat invasion and renal vein
invasion, sensitivity values were 15.4% and 11.3%, respectively. Out
of 383 radiological stage III cases, concordant pathology was found in
185 (48.3%). Of 2658 radiologically localized tumors (stage I or II),
464 (17.5%) identified as up-staged to stage III after nephrectomy
(Table 2). Positive surgical margins (PSM) were found in 39 (8.4%) of
464 up-staged patients and 23 (12.4%) of 185 concordant pathology cases
(p=0.08).