Age (year) |
69.75±12.00 |
69.80±7.79 |
69.70±15.60 |
0.99 |
Gender |
Gender |
Gender |
Gender |
Gender |
Male
|
8 (40%)
|
3 (30%)
|
5 (50%)
|
0.65
|
Female
|
12 (60%)
|
7 (70%)
|
5 (50%)
|
|
Weight (kg) |
65.15±6.28 |
61.70±2.36 |
68.60±7.15 |
0.01 |
BMI |
24.45±1.84 |
24.12±2.03 |
24.78±1.67 |
0.44 |
Comorbidities |
Comorbidities |
Comorbidities |
Comorbidities |
Comorbidities |
COPD
|
2 (10%)
|
1 (10%)
|
1 (10%)
|
1
|
Chronic kidney disease
|
1 (5%)
|
0 (0%)
|
1 (10%)
|
1
|
Cardiovascular disease
|
4 (20%)
|
2 (20%)
|
2 (20%)
|
1
|
Hypertension
|
11 (55%)
|
6 (60%)
|
5 (50%)
|
1
|
Diabetes
|
3 (15%)
|
2 (20%)
|
1 (10%)
|
1
|
Cerebral vascular disease
|
2 (10%)
|
1 (10%)
|
1 (10%)
|
1
|
Clinical manifestations and signs |
Clinical manifestations and signs |
Clinical manifestations and signs |
Clinical manifestations and signs |
Clinical manifestations and signs |
Fever
|
17 (85%)
|
8 (80%)
|
9 (90%)
|
1
|
Cough
|
19 (95%)
|
10 (100%)
|
9 (90%)
|
1
|
Dyspnea
|
16 (80%)
|
10 (100%)
|
6 (60%)
|
0.09
|
Fatigue or myalgia
|
18 (90%)
|
10 (100%)
|
8 (80%)
|
0.47
|
Diarrhea
|
3 (15%)
|
1 (10%)
|
2 (20%)
|
1
|
Vital Signs |
Vital Signs |
Vital Signs |
Vital Signs |
Vital
Signs |
Oxygen saturation (%)
|
85.55 ±10.30
|
(84.10±13.82)
|
(89.00±4.42)
|
0.3
|
Respiratory rate
|
29.30±7.21
|
30.70±8.17
|
27.90±6.21
|
0.4
|
Respiratory rate > 24/min
|
14 (70%)
|
7 (70%)
|
7 (70%)
|
1
|
Heart rate
|
97.95±16.72
|
99.50±16.94
|
96.40±17.25
|
0.69
|
GCS score
|
13.65±2.01
|
14.69±0.70
|
12.70±2.45
|
0.03
|
Duration |
Duration |
Duration |
Duration |
Duration |
Days from onset to ICU admission
|
11.15±9.45
|
8.10±9.47
|
14.20±8.93
|
0.16
|
Days in the general ward prior to ICU admission
|
5.55±6.86
|
4.50±5.78
|
6.60±7.96
|
0.51
|
Days from onset to hospitalization
|
9.35±6.34
|
8.20±3.08
|
10.50±8.52
|
0.43
|
Days from onset to dyspnea
|
9.95±6.63
|
7.22±7.50
|
12.40±4.89
|
0.09
|
Laboratory indicators |
Laboratory indicators |
Laboratory indicators |
Laboratory indicators |
Laboratory indicators |
WBC (×109/L)
|
8.70±5.13
|
9.12±5.87
|
8.29±4.56
|
0.73
|
< 4
|
1 (5%)
|
0 (0%)
|
1 (10%)
|
1
|
4-10
|
14 (70%)
|
8 (80%)
|
6 (60%)
|
0.63
|
> 10
|
5 (25%)
|
2 (20%)
|
3 (30%)
|
1
|
NEU (%)
|
82.40±10.44
|
80.70±9.11
|
84.10±11.86
|
0.48
|
Lymphocyte count (×109/L)
|
0.95±0.91
|
1.01±0.49
|
0.89±1.22
|
0.78
|
< 0.8
|
11 (55%)
|
3 (30%)
|
8 (80%)
|
0.07
|
Hemoglobin (g/L)
|
128.20±18.49
|
126.60±14.19
|
126.80±22.68
|
0.71
|
Anemia
|
3 (15%)
|
1 (10%)
|
2 (20%)
|
1
|
PT (s)
|
13.76±1.10
|
13.70±1.07
|
13.82±1.19
|
0.81
|
APTT (s)
|
95.26±18.18
|
94.83±15.30
|
95.70±21.53
|
0.92
|
D-Dimer (mg/mL)
|
6.91±11.17
|
5.16±7.46
|
8.65±14.17
|
0.5
|
> 0.5 to ≤1
|
5 (25%)
|
2 (20%)
|
3 (30%)
|
1
|
> 1
|
15 (75%)
|
8 (80%)
|
7 (70%)
|
1
|
ALT (U/L)
|
59.96±96.75
|
73.30±129.15
|
46.60±51.82
|
0.55
|
> 40
|
6 (30%)
|
3 (30%)
|
3 (30%)
|
1
|
AST (U/L)
|
69.75±83.40
|
41.80±30.07
|
97.70±109.74
|
0.14
|
> 40
|
8 (40%)
|
3 (30%)
|
5 (50%)
|
0.66
|
TBIL (μmol/L)
|
13.62±7.89
|
12.69±4.80
|
14.55±10.32
|
0.61
|
> 17.1
|
2 (10%)
|
1 (10%)
|
1 (10%)
|
1
|
Albumin (g/L)
|
34.92±2.77
|
34.92±3.35
|
34.91±2.23
|
0.99
|
BUN (μmol/L)
|
7.22±3.81
|
5.76±3.03
|
8.69±4.08
|
0.09
|
> 7.1
|
10 (50%)
|
4 (40%)
|
6 (60%)
|
0.66
|
CK (U/L)
|
96.15±52.84
|
100.90±47.30
|
91.40±60.05
|
0.7
|
> 185
|
2 (10%)
|
1 (10%)
|
1 (10%)
|
1
|
CK-MB (U/L)
|
16.40±8.59
|
17.70±9.33
|
15.10±8.06
|
0.51
|
LDH (U/L)
|
539.15±455.85
|
574.30±604.95
|
504.0±264.52
|
0.74
|
> 245
|
17 (85%)
|
9 (90%)
|
8 (80%)
|
1
|
BNP (pg/mL)
|
5696.53±8832.56
|
2991.77±2441.31
|
8401.28±11936.46
|
0.18
|
> 400
|
15 (75%)
|
8 (80%)
|
7 (70%)
|
1
|
CRP (mg/L)
|
101.46±65.60
|
114.58±74.25
|
88.33±56.47
|
0.39
|
ProCT (ng/mL)
|
0.31±0.42
|
0.37±0.58
|
0.25±0.14
|
0.53
|
<0.1
|
3 (15%)
|
2 (20%)
|
1 (10%)
|
1
|
0.1-0.25
|
8 (40%)
|
4 (40%)
|
4 (40%)
|
1
|
0.25-0.5
|
7 (35%)
|
3 (30%)
|
4 (40%)
|
1
|
≥0.5
|
2 (10%)
|
1 (10%)
|
1 (10%)
|
1
|