Figure 1: model for the eosinophil compartment in
humans. Eosinophils are produced in the bone marrow and released into
the blood as mature cells. Two separate differentiation paths seem to be
present: one IL-5 dependent2 ,leading to inflammatory
cells and one IL-5 independent7 ,leading to resident
cells. In contrast to inflammatory cells, resident eosinophils are
present in healthy individuals at rather stable numbers of ±100
cells/µl8.