Decreased macrophages in spleens after M2 macrophage treatment
The macrophage percentages in the spleens were higher in EAE groups than that in M2-treated group at the peak of the EAE(P< 0.0001). The percentage of M1 macrophages was lower in the M2-treated group than in EAE group(P<0.05). The M2 macrophages were lower in the M2-treated group than in EAE group(P<0.0001).(Figure 3a)