Author contributions
SAC-S, VFL, JG and DMD designed the research and experiments. SAC-S and VFL performed the experiments. Mass spectrometry analysis was carried out by LPS, with the supervision of ARF. Analysis of metabolomics data was carried out by SAC-S. Data analysis and interpretation and the establishment of figures were carried out by SAC-S, VFL, FBSF and DMD. All authors contributed to writing the manuscript. DMD obtained funding and is responsible for this article.