Genome-wide association study of asthma at 5 years. a) Manhattan plot showing one SNV on chromosome 1q32.1 associated with asthma in the multi-ethnic CHILD Study Cohort (p < 5e-8). Y-axis depicts the -log10 transformed p-value and x-axis shows chromosomal positions. Suggestive significance (p=5e-5) and genome-wide significance (p=5e-8) are respectively marked as blue and red horizontal lines, respectively. b) Manhattan plot showing one SNV on chromosome 1q32.1 associated with asthma diagnosis in the Central European CHILD Study Cohort (p < 5e-8). Y-axis depicts the -log10 transformed p-value and x-axis shows chromosomal positions. Suggestive significance (p=5e-5) and genome-wide significance (p=5e-8) are respectively marked as blue and red horizontal lines, respectively.