Table 3. Clinical phenotypes of viral reactivation among DRESS patients Table 3. Clinical phenotypes of viral reactivation among DRESS patients Table 3. Clinical phenotypes of viral reactivation among DRESS patients Table 3. Clinical phenotypes of viral reactivation among DRESS patients Table 3. Clinical phenotypes of viral reactivation among DRESS patients Table 3. Clinical phenotypes of viral reactivation among DRESS patients
Phenotypes
Viral Reactivation
Viral Reactivation
Total (N=93)
Univariate Analysis
Univariate Analysis
No (N=54) Yes (N=39) Unadjusted OR* (95% CI)
p-value
Fever > 38.5 °C, n(%) 34 (63.0) 28 (71.8) 62 (66.7) 1.5 (0.6 to 3.7) 0.37
Lymphadenopathy, n(%) 17 (31.5) 7 (17.9) 24 (25.8) 0.5 (0.2 to 1.3) 0.15
Blood involvement, n(%) 53 (98.1) 39 (100) 92 (98.9) NE 0.99
Eosinophilia 46 (85.2) 35 (89.7) 81 (87.1) 1.5 (0.4 to 5.5) 0.52 1.5 (0.4 to 5.5) 0.52
Atypical Lymphocytes 46 (85.2) 36 (92.3) 82 (88.2) 2.1 (0.5 to 8.4) 0.30
Organ Involvement, n(%)
1 organ involved 23 (48.9) 11 (29.7) 34 (40.5) Reference
2 organs involved 12 (27.7) 12 (32.4) 25 (29.8) 1.9 (0.7 to 5.6)
3 organs involved 6 (12.8) 4 (10.8) 10 (11.9) 1.4 (0.3 to 6.0) 0.16+
> 3 organs involved 5 (10.6) 10 (27.0) 15 (17.9) 4.2 (1.2 to 15.2)
Liver 39 (72.2) 28 (71.8) 67 (72.0) 1.0 (0.4 to 2.5) 0.96
Kidney 19 (35.2) 22 (56.4) 41 (44.1) 2.4 (1.0 to 5.5) 0.04
Lungs 05 (9.3) 06 (15.4) 11 (11.8) 1.8 (0.5 to 6.3) 0.37
Heart 07 (13.0) 10 (25.6) 17 (18.3) 2.3 (0.8 to 6.8) 0.13
Pancreas 03 (5.6) 03 (7.7) 06 (6.5) 1.4 (0.3 to 7.4) 0.68
Gastrointestinal 07 (13.0) 07 (17.9) 14 (15.1) 1.5 (0.5 to 4.6) 0.51
Thyroid 8 (14.8) 10 (25.6) 18 (19.4) 2.0 (0.7 to 5.6) 0.20
Others* 5 (9.3) 08 (20.5) 13 (14.0) 2.5 (0.8 to 8.4) 0.13
NE: Not estimable * Note: Other organ involvements include (patients): central nervous system (8), gallbladder (3), aorta (1), spleen (1) NE: Not estimable * Note: Other organ involvements include (patients): central nervous system (8), gallbladder (3), aorta (1), spleen (1) NE: Not estimable * Note: Other organ involvements include (patients): central nervous system (8), gallbladder (3), aorta (1), spleen (1) NE: Not estimable * Note: Other organ involvements include (patients): central nervous system (8), gallbladder (3), aorta (1), spleen (1) NE: Not estimable * Note: Other organ involvements include (patients): central nervous system (8), gallbladder (3), aorta (1), spleen (1) NE: Not estimable * Note: Other organ involvements include (patients): central nervous system (8), gallbladder (3), aorta (1), spleen (1)