Results
Overall, 100 patients fulfilled the case criteria. Ninety-three patients
had at least one viral marker tested. HHV6, EBV and CMV reactivation
occurred in 24 out of 85 cases (28%), 15 out of 87 (17%) cases, and 18
out of 89 (20%) cases respectively. Viral reactivation cases were
associated with higher 1-year mortality, dialysis initiation, recurrent
flares of disease, and longer hospital stay (all p<0.05). Risk
of inpatient mortality (OR, 5.8; 95% CI, 1.7-20.7; p<0.01)
and 1-year mortality (OR, 10.0, 95% CI, 2.9-34.9; p<0.01)
increased with multiple viral reactivations. Viral reactivation was
independent of demographics, comorbidities, treatment or causative drug.