Conclusion
Biological prosthesis valve dysfunction is a clinically significant process. It has become a major issue considering the growing rate of bioprosthesis implantation and improved long-term patient survival. Research on the field has improved in the past few years but there is still not an ideal bioprosthesis. Understanding bioprosthetic aortic valve degeneration from a basic science perspective is a key point to improve technologic advances and specifications that lead to new generation of bioprosthesis.
Key-words: bioprosthetic, valve repair/ replacement, valve dysfunction, immunology, inflammation