Conclusions
This study provides information which may be of use for clinicians when advising families of infants with CNLD being discharged on home supplemental oxygen therapy. Shorter length of initial NICU stay appears to predict shorter duration of home oxygen therapy and was associated with lower odds of needing ≥ 200 mL/min at discharge. Infants with higher CGA at discharge or hypercarbia were more likely to need higher levels of home oxygen therapy. Close monitoring is recommended for infants discharged on higher flows of oxygen therapy (e.g. >250 mL/min) as these infants have a higher risk of respiratory related hospital and PICU admissions within the first two years. Additionally, our study highlights the variability in practice and need for standardization of oxygen weaning process for infants with CNLD in order to improve outcomes for this increasing population.