2.3. Risk of bias – study quality assessment
Risk of bias in individual studies was assessed independently by two
investigators. Discrepancies were
resolved through discussion between
three investigators. RCTs were
assessed using the revised Cochrane collaboration Risk of Bias tool 2
for randomized controlled trials (RoB2) 15, and NRSI
were assessed using Cochrane collaboration Risk of bias in
non-randomized studies of interventions (ROBINS-I) tool (see Supplement
for details) 16.