Condensed abstract
Catheter ablation is an established, effective approach for the treatment of AF in patients with heart failure, however the role of cryoablation in this setting is unclear. Procedural success and LVEF improvement in patients with LVEF≤45% undergoing index catheter ablation with cryoablation were evaluated. Freedom from AF recurrence was seen in 43% rising to 59% following repeat procedure. There were significant improvements in LVEF and functional status at long-term follow up. Cryoablation is an effective first-line AF ablation approach in the setting of heart failure.