Figure legends
Fig. 1 Structures of S-Oxiracetam(A), R-Oxiracetam(B) and
Piracetam (C, internal standard)
Fig. 2 Design and subject allocation scheme for single-dose
study in part 1, for chiral pharmacokinetic comparative study in part 2
and for multiple-dose study in part 3
Fig. 3 Mean plasma concentration-time profiles of S-ORT in
three single-dose groups (n=10 for each dose group) (arithmetic scale on
the left and logarithmic scale on the right)
Fig. 4 Profile of 48 hours cumulative urine excretion rate
after single-dose administration of 4.0 g S-ORT, n=10
Fig. 5 Mean plasma concentration-time profiles following
multiple-dose administration of 4.0 g S-ORT on day 1 and day 7, n=10
Fig. 6 Mean plasma concentrations-time profiles of S-ORT and
R-ORT after a single-dose intravenous infusion of 6.0 g racemic ORT
injection, n=12 (arithmetic scale on the left and logarithmic scale on
the right)