Impact statement
This is the first case series of exercise-induced allergic reaction on desensitization (EIARD) after the implementation of slow oral immunotherapy (OIT) for wheat and cow’s milk. Although this study was conducted in a retrospective manner, the strength of this study is that the diagnosis of EIARD was based on the exercise provocation tests (EPTs). We found that EIARDs occur not only after rush OIT for wheat11, but also after slow OIT for cow’s milk and wheat.