Risk factors of EIARD
The following clinical information was collected as potential factors
associated with EIARD: age at the start of OIT and at EPT; history of
other allergic diseases; average pace of increasing the amount of
antigen during OIT (defined as the difference between the full dose and
the starting dose, divided by the duration of OIT); and specific IgE
(sIgE) titer (milk and casein, or wheat and ω-5 gliadin) before starting
OIT and within 1 year before the EPT (after OIT).
sIgE levels were detected using
ImmunoCAP® (Thermo Fisher Scientific, Uppsala,
Sweden). A level of ≤0.34 kUA/L was fixed at 0.34 kUA/L, indicating no
sensitization. Levels >100 kUA/L were fixed at 100 kUA/L.