RESULTS
The analytic cohort included 61 families with evaluable self-report
adherence data (Table 1). Fifteen (25%, [95% CI, 14-37%])
patients met the study definition of 6MP non-adherence. Twenty-five
percent did not have a medication-taking routine. Paternal education
level differed significantly between adherent and non-adherent patients.
Of the group of fathers who completed high school or more 81% were
adherent compared to only 43% who did not complete high school
(p=0.045). Five percent of participants endorsed difficulty paying for
their 6MP, however this was not associated with non-adherence.
When asked “what would happen if your child stopped taking 6MP,” only
N= 30 (49% [95% CI, 36-62%]) parents reported “relapse” or
“cancer returning.” The most common reasons for missing 6MP were
related to dosing restrictions around food or falling asleep prior to
bedtime dose administration. Fourteen (23% [95%CI 13-36%])
parents reported that it was “not easy” to follow 6MP administration
guidelines. Across the full cohort, N= 24 (39% [95% CI 27-53%])
participants suggested that printed calendars would help with adherence
and N=35 (57% [95% CI, 44-70%]) expressed interest in receiving
educational resources about 6MP