CONCLUSION
According to the results of our study, it can be clearly said that thiol
/ disulphide homeostasis is affected in lung tuberculosis. This may play
a role in the pathogenesis of this disease, and measuring this
parameters can provide an overview for understanding the disease
process. To our knowledge, our study is the first to evaluate the dynamic
thiol–disulphide homeostasis in the serum of patients with lung
tuberculosis. The results of our study showed that this newly developed
test can be used as an assayed, accurate and novel oxidative stress
marker in the pathogenesis of lung tuberculosis. Evaluation of
thiol/disulfide parameters in lung tuberculosis patients can make a
significant contribution to assessing and monitoring patients with lung
tuberculosis patients. There is a need for new studies that will show
the possible effects of oxidative stress on lung tuberculosis
pathogenesis.