Background
Systemic capillary leak syndrome (SCLS) is a very serious condition of unknown cause, first reported by Clarkson in 1960 (1). The characteristics of SCLS are hypotension, hemoconcentration, and low plasma albumin levels; however, there are no clear diagnostic criteria (2-13). Certain autoimmune systems may be involved in the disease. Various treatments have been attempted, including fluid resuscitation, renal replacement therapy, corticosteroid administration, high-dose intravenous immunoglobulin (IVIG), and plasma exchange (PE) (4-6). We present a case of SCLS that developed after surgery for colon cancer perforating peritonitis wherein we treated the patient with plasma filtration with dialysis (PDF). Moreover, we obtained new information about this condition during the course of treatment.