Abstract
We describe six teenagers
presenting with fever and severe abdominal symptoms admitted with
concerns for multisystem inflammatory syndrome in children (MIS-C).
Laboratory evaluation revealed elevated markers of inflammation,
lymphopenia, and increased d-dimers. Imaging studies revealed multifocal
airspace disease and ground-glass opacities. SARS-CoV-2 PCR and
serologies were negative. All patients reported a history of vaping,
prompting E-cigarette, or vaping,
product use-associated lung injury (EVALI) diagnosis. MIS-C has
overlapping clinical and laboratory features highlighting the added
challenge of diagnosing EVALI during the COVID-19 pandemic.