Effects of geohelminths on secondary outcomes
There were no significant associations of geohelminths with airways
reactivity, FeNO and nasal eosinophilia (Figure 2 and supplementary
Table 3). When considering parasite species and burden, elevated FeNO
was associated with moderate/heavy parasite burdens with A.
lumbricoides both in mothers (vs. uninfected, adj. OR 2.19, 1.23-3.90,
P=0.008) and children at 5 years (vs. uninfected, adj. OR 2.27,
1,10-4.70, P=0.027). After co-adjusting for maternal and child infection
intensities, only the maternal effect remained significant (vs.
uninfected, adj. OR 2.20, 95% CI 1.16-4.19, P=0.016).