The endocannabinoid signaling system (ECS) includes the cannabinoid receptor type 1 (CBR1) and type 2 (CBR2), along with their endogenous ligands (arachidonoylethanolamide and 2-arachidonoyl glycerol) for the cannabinoid receptors. THC (Δ9-tetrahydrocannabinol) is one of the best-known exogenous activators of the CBR1 and CBR2. It is found in Cannabis sativa (marijuana), widely recognised as a psychoactive agent. Signaling pathways mediated by the cannabinoid receptor (CBR) may affect cell proliferation, differentiation, and apoptosis in animal and human cells [15–17].