Some researchers conducted studies on CBR expression in the human model analyzing its role in the inflammatory processes in patients with endometriosis [35,36,41,42]. Bouaziz et al. established that cannabinoids might be a highly effective treatment for women with endometriosis because of their complex action: the effect on the central and peripheral nervous system, suppression of neuropathic and inflammatory pain, psychological impact, the levels of hormones affecting the perception of pain, and the effect on the expression of CBRs, enzymes, and ligands [43].