Furthermore, based on a study conducted in humans, it seems that a decrease in CBR1 and CBR1a mRNA levels might be connected with placental disorders, such as preterm placental abruption, leading to preterm deliveries or the intrauterine death of the fetus [48]. However, our study did not show such effects, as no changes in intrapartum CBR mRNA levels were observed, indicating a complex interaction that warrants further investigation.