Inflammation is a crucial factor in both PTB and term birth [10]. Although a higher concentration of inflammatory cytokines was found in the amniotic fluid following delivery [11], Raba et al. observed that inflammatory cytokines played a crucial role in over 80% of PTB cases, particularly in those occurring before 30 weeks of gestation [12]. Other causes of PBT include premature rupture of the membranes caused by an infection of the amniotic sac or alterations in vaginal bacterial flora [13,14].