Papermill provides a mechanism to execute a Jupyter Notebook either while inserting a particular parameter set into a copy of the Notebook prior to execution. By tagging a particular Notebook cell with the “parameters” tag, Papermill uses that tag to do a value substitution for any variables defined in that cell with the execution parameters provided.  This is a natural fit for exploring parameter spaces in tomographic analysis, where one may need to experiment with different combinations of parameters to determine the best fit for the data at hand.