Introduction
Cryptococcosis is one of the common mycological condition leading to
morbidity and mortality in patients with AIDS.1Cryptococcus can cause life threatening infections like
meningoencephalitis and disseminated cryptococcosis in immunocompromised
patients.2 According to the studies, 10 to 25% of
AIDS patients with cryptococcosis die even if they have received
antifungal therapy and 30 to 60% die within the first year of onset of
the infection.1
We present a case of disseminated cryptococcosis in a patient with HIV,
which were both diagnosed by clinical autopsy using Minimally Invasive
Tissue Sampling (MITS) technique.3 In Nepal, clinical
autopsies are not usually conducted and forensic autopsies are not
routinely backed up with histopathological, microbiological and other
ancillary tests. In this case, we performed MITS procedure along with
histopathological, serological and microbiological tests as a part of a
research project – Determining Efficiently the Cause of Death among
Adults and Generating Mortality Evidence at MITS Alliance Unit Nepal
(DECODE MAUN Nepal).