Author Contributions
LMD, DAR, DDMS conceived of the study; DAR, JHP, LRY, SJR and HZ collected samples; DAR, DDMS, ECT, GM, JHP, KTJD, LMD, LRY, PD, SJR, SV, YTGG and ZH generated data; AMB, APC, DDMS, GH, LMD, TML, YTGG and ZH analyzed data guided, in part, by DAR and FGH; APC, DAR, DDMS, LMD and TML wrote the manuscript. All authors reviewed the manuscript prior to submission.