Conclusion:
Significant BD response in hospitalized children treated for a CF pulmonary exacerbation is rare, is not related to age, severity of lung disease or potential recovery of lung function, and does not lead to immediate changes in clinical management in the majority of patients. BD response is poorly related to baseline, and recovery of FEV1. These data suggest that routine testing of bronchodilator response during CF PEx is not indicated, and should be limited to selected patients when clinically needed.