Conclusion:
Significant BD response in hospitalized children treated for a CF
pulmonary exacerbation is rare, is not related to age, severity of lung
disease or potential recovery of lung function, and does not lead to
immediate changes in clinical management in the majority of patients. BD
response is poorly related to baseline, and recovery of
FEV1. These data suggest that routine testing of
bronchodilator response during CF PEx is not indicated, and should be
limited to selected patients when clinically needed.