Introduction
Graft-versus-host disease (GVHD) is a potentially serious complication
of allogenic stem cell transplantation (allo-SCT), but patients who
develop GVHD also have a low incidence rate of leukemia recurrence,
suggesting a graft-versus-leukemia effect due to the donor
lymphocytes.1 This effect has also been suggested in
solid tumors. In the case here, cervical cytology transformed from
squamous cell carcinoma to negative for intraepithelial lesion or
malignancy (NILM), possibly due to a graft-versus-tumor (GVT) effect
following allo-SCT. The cervical cytology has continued changing,
although the dose of immunosuppressant likely also has an effect. Here
we describe our experience in this case and review the literature.