STUDY LIMITATIONS
Our study has several limitations with a single center and small patient group. Because of our small amount of patients, the study had only 9 indeterminate patients, so we could not demonstrate whether LV GLS is adequate to define diastolic dysfunction in those patient groups. Besides, all standard echocardiographic measurements and LV GLS were performed in resting, so we could not assess the relationship between LV GLS and impaired functional capacity, which is the highly essential hallmark for HFpEF. Future studies with a multicenter design and a larger study population will be essential to demonstrate the additional effects of GLS on the 2016 ASE/EACVI algorithm as well as on the HFA-PEFF algorithm