Patients Characteristics and Clinical Courses
Sixteen patients were enrolled in this study (Table 1). The age at diagnosis ranged from 4 months to 11 years. Of the 16 patients, 10 had pulmonary metastasis or metastases at the initial hospital visit. The period from initial diagnosis of hepatoblastoma to the diagnosis of pulmonary metastasis was 0–30 months. The observation period of the patients from the initial diagnosis was 2–55 months (median, 46 months). Three patients died of the disease and thirteen are still alive.