3.3.3 | Need for mechanical ventilation within 72 h of life
Eight trials 14,16-18,20,21,24,26 showed data on the requirement of mechanical ventilation within 72 h of life with a total of 892 infants. Meta-analysis revealed that infants in the MISA group required less mechanical ventilation within 72 h of life (RR : 0.60, 95% CI : 0.48 to 0.75, I2 = 36%, p < .00001). Sensitivity analysis showed similar results (RR : 0.76, 95% CI : 0.58 to 0.99, I2 = 0%, p = .04, 7 studies16-18,20,21,24,26 (n = 672)) (Figure 2C).