3.3.2 | BPD at 36 weeks
Twelve trials 14-21,23-26 involving 1831 newborns reported the incidence of BPD at 36 weeks. Meta-analysis revealed that MISA techniques brought about a significant decrease in this outcome (RR : 0.59, 95% CI : 0.46 to 0.75, I2 = 3%, p < .0001). Sensitivity analysis limited to studies that unequivocally stated the use of the INSURE regimen in the control group showed similar results (RR : 0.59, 95% CI : 0.45 to 0.78, I2 = 20%, p = .0002, 10 studies15-18,20,21,23-26 (n = 1400)) (Figure 2B).