Response to Induction Therapy
At the end of Induction, 112/118 (94.9%) of iCNS-R patients attained remission, with one induction failure, 2 induction deaths (influenza A H1N1 and Pseudomonas jirovecii pneumonia with acute respiratory distress syndrome), and 3 patients removed from therapy due to toxicity and/or physician discretion (Figure 1 ).