Conclusion
This review presented an overview of available studies on social isolation, adverse effects on cognition, and possible treatments. A wide range of studies have been collected and retrieved to explain beneficial treatment methods. Learning and memory impairments, anxiety and depressive-like behaviors, and social deficit consequences of social isolation have improved by prescription of some opioid drugs, anti-depressants, antipsychotics, and a variety of antagonists. Moreover, Antioxidants and Herbal medications have found helpful to ameliorate isolation side effects. Besides, an enriched environment, regular exercise, and music, as non-drug treatments, have shown to be beneficial for isolated people. Finally, the application of technology and farming activities have suggested improving isolation-induced cognitive and social impairments.