References
  1. Baker, J. K., & Myers, C.W. (1991). One-dimensional and two-dimensional 1H- and13C-nuclear magnetic resonance (NMR) analysis of vitamin E raw materials or analytical reference standards.Pharmaceutical Research , 8 :763–770. https://doi.org/10.1023/A:1015810303089
  2. Birringer, M., Siems, K., Maxones, A., Frank, J., & Lorkowski, S. (2018). Natural 6-hydroxy-chromanols and -chromenols: structural diversity, biosynthetic pathways and health implications. RSC Advances , 8 :4803–4841. https://doi.org/10.1039/C7RA11819H
  3. Butinar, B., Bučar-Miklavčič, M., Mariani, C., & Raspor, P. (2011). New vitamin E isomers (gamma-tocomonoenol and alpha-tocomonoenol) in seeds, roasted seeds and roasted seed oil from the Slovenian pumpkin variety ‘Slovenska golica. Food Chemistry,128 :505–512. https://doi.org/10.1016/j.foodchem.2011.03.072
  4. Deutsche Gesellschaft für Ernährung (DGE), Österreichische Gesellschaft für Ernährung (ÖGE), Schweizerische Gesellschaft für Ernährung (SGE). (2018). D-A-CH-Referenzwerte für die Nährstoffzufuhr (2nd ed., 4th updated version). Bonn, Germany. Retrieved from https://www.dge.de/wissenschaft/referenzwerte/vitamin-e/?L=0
  5. Englert, M., Brown L., & Vetter, W. (2015). Heart-cut two-dimensional countercurrent chromatography with a single instrument.Analytical Chemistry , 87 :10172–10177. https://doi.org/10.1021/acs.analchem.5b02859
  6. Fiorentino, A., Mastellone, C., D’Abrosca, B., Pacifico, S., Scognamiglio, M., Cefarelli, G., Caputo, R., & Monaco, P. (2009). δ-Tocomonoenol. A new vitamin E from kiwi (Actinidia chinensis ) fruits. Food Chemistry , 115 :187–192. https://doi.org/10.1016/j.foodchem.2008.11.094
  7. Fruhwirth, G., & Hermetter, A. (2008). Production technology and characteristics of Styrian pumpkin seed oil. European Journal of Lipid Science and Technology , 110 :637–644. https://doi.org/10.1002/ejlt.200700257
  8. Gee, P. T., Liew, C. Y., Thong, M. C., & Gay, M. C. L. (2016). Vitamin E analysis by ultra-performance convergence chromatography and structural elucidation of novel α-tocodienol by high-resolution mass spectrometry. Food Chemistry , 196 :367–373. https://doi.org/10.1016/j.foodchem.2015.09.073
  9. Goad, J. L., & Akihisa, T. (1997). Analysis of sterols (1st ed.). London, UK:Blackie Academic & Professional.
  10. Goh, S. H., Hew, N. F., Norhanom, A. W., & Yadav, M. (1994). Inhibition of tumour promotion by various palm-oil tocotrienols.International Journal of Cancer , 57 :529–531. https://doi.org/10.1002/ijc.2910570415
  11. Hammann, S., Englert, M., Müller, M., & Vetter, W. (2015). Accelerated separation of GC-amenable lipid classes in plant oils by countercurrent chromatography in the co-current mode.Analytical and Bioanalytical Chemistry , 407 :9019–9028. https://doi.org/10.1007/s00216-015-9068-5
  12. Hammann, S., Korf, A., Bull, I. D., Hayen, H., & Cramp, L. J. E. (2019). Lipid profiling and analytical discrimination of seven cereals using high temperature gas chromatography coupled to high resolution quadrupole time-of-flight mass spectrometry. Food Chemistry ,282 :27–35. https://doi.org/10.1016/j.foodchem.2018.12.109
  13. Hammann, S., Kröpfl, A., & Vetter, W. (2016). More than 170 polyunsaturated tocopherol-related compounds in a vitamin E capsule: countercurrent chromatographic enrichment, gas chromatography/mass spectrometry analysis and preliminary identification of the potential artefacts. Journal of Chromatography A , 1476 :77–87. https://doi.org/10.1016/j.chroma.2016.11.018
  14. Hammann, S., Tillmann, U., Schröder, M., & Vetter, W. (2013). Profiling the fatty acids from a strain of the microalgaeAlexandrium tamarense by means of high-speed counter-current chromatographyand gas chromatography coupled with mass spectrometry.Journal of Chromatography A , 1312 :93-103. https://doi.org/10.1016/j.chroma.2013.08.090
  15. Hammann, S., Wendlinger, C., & Vetter, W. (2015). Analysis of intact cholesteryl esters of furan fatty acids in cod liver. Lipids ,50 :611–620. https://doi.org/10.1007/s11745-015-4019-7
  16. Irías-Mata, A., Sus, N., Hug, M.-L., Müller, M., Vetter, W., & Frank, J. (2020). α-Tocomonoenol is bioavailable in mice and may partly be regulated by the function of the hepatic α-tocopherol transfer protein. Molecules , 25 :4803. https://doi.org/10.3390/molecules25204803
  17. IUPAC-IUB Joint Commission on Biochemical Nomenclature. Nomenclature of tocopherols and related compounds. (1982). Pure and Applied Chemistry , 54:1507–1510.
  18. Kamal-Eldin, A., & Appelqvist, L-Å. (1996). The chemistry and antioxidant properties of tocopherols and tocotrienols. Lipids ,31 :671–701. https://doi.org/10.1007/BF02522884
  19. Kruk, J., Pisarski, A., & Szymańska, R. (2011). Novel vitamin E forms in leaves of Kalanchoe daigremontiana and Phaseolus coccineus . Journal of Plant Physiology ,168 :2021–2027. https://doi.org/10.1016/j.jplph.2011.06.015
  20. Lee, H., Finckbeiner, S., Yu, J. S., Wiemer, D. F., Eisner, T., & Attygalle, A. B. (2007). Characterization of (E,E)-farnesol and its fatty acid esters from anal scent glands of nutria (Myocastor coypus ) by gas chromatography–mass spectrometry and gas chromatography–infrared spectrometry.Journal of Chromatography A , 1165 :136–143. https://doi.org/10.1016/j.chroma.2007.06.041
  21. Mariani, C., & Bellan, G. (1996). Content of tocopherols, deidrotocopherols, tocodienols, tocotrienols in vegetable oils.Rivista Italiana delle Sostanze Grasse , 73 :533–543.
  22. Matsumoto, A., Takahashi, S., Nakano, K., & Kijima, S. (1995). Identification of new vitamin E in plant oil. Journal of Oleo Science , 44 :593–597.
  23. Merza, J., Aumond, M.-C., Rondeau, D., Dumontet, V., Le Ray, A.-M., Se´raphin, D., & Richomme, P. (2004). Prenylated xanthones and tocotrienols from Garcinia virgata . Phytochemistry ,65 :2915–2920. https://doi.org/10.1016/j.phytochem.2004.06.037
  24. Miyazawa, T., Tszuzuki, T., Nakagawa, K., & Igarashi, M. (2004). Antiangiogenic potency of vitamin E. Annals of the New York Academy of Sciences, 1031 : 401–404. https://doi.org/10.1196/annals.1331.057
  25. Müller, M., Hammann, S., & Vetter, W. (2018). Countercurrent chromatographic isolation and purification of 11′-α-tocomonoenol from the vitamin E extract of palm oil. Food Chemistry ,256 :327–332. https://doi.org/10.1016/j.foodchem.2018.02.133
  26. Müller, M., Kröpfl, A., & Vetter, W. (2020). Identification of two α-tocodienol isomers in palm oil after countercurrent chromatographic enrichment. Analytical and Bioanalytical Chemist ,412 :795–802. https://doi.org/10.1007/s00216-019-02303-1
  27. Müller, M., Muric, M., Glanz, L., & Vetter, W. (2019). Improving the resolution of overlapping peaks by heartcut two-dimensional countercurrent chromatography with the same solvent system in both dimensions. Journal of Chromatography A ,1596 :142–151. https://doi.org/10.1016/j.chroma.2019.03.012
  28. Ng, M. H., Choo, Y. M., Ma, A. N., Chuah, C. H., & Hashim, M. A. (2004). Separation of vitamin E (tocopherol, tocotrienol, and tocomonoenol) in palm oil. Lipids , 39 :1031–1035. https://doi.org/10.1007/s11745-004-1327-y
  29. Ohnmacht, S., West, R., Simionescu, R., & Atkinson, J. (2008). Assignment of the 1H and 13C NMR of tocotrienols. Magnetic Resonance in Chemistry ,46 :287–294. https://doi.org/10.1002/mrc.2176
  30. Prasad, K. (2011). Tocotrienols and cardiovascular health.Current Pharmaceutical Design , 17 :2147–2154. https://doi.org/10.2174/138161211796957418
  31. Puah, W. C., Choo, M. Y., Ma, N. A., & Chuah, H. C. (2007). The effect of physical refining on palm vitamin E (tocopherol, tocotrienol and tocomonoenol). American Journal of Applied Sciences ,4 :374-377.
  32. Saremi, A., & Arora, R. (2010). Vitamin E and cardiovascular disease.American Journal of Therapeutics , 17 :56–65. https://doi.org/10.1097/MJT.0b013e31819cdc9a
  33. Schröder, M., & Vetter, W. (2012). Investigation of unsaponifiable matter of plant oils and isolation of eight phytosterols by means of high-speed counter-current chromatography. Journal of Chromatography A , 1237 :96-105. https://doi.org/10.1016/j.chroma.2012.03.033
  34. Sen, C.K., Khanna, S., & Roy, S. (2006). Tocotrienols: vitamin E beyond tocopherols. Life Sciences , 78 :2088–2098. https://doi.org/10.1016/j.lfs.2005.12.001
  35. Van Hoed, V., Depaemelaere, D., Ayala, J. V., Santiwattana, P., Verhé, R., & DeGreyt, W. (2006). Influence of chemical refining on the major and minor components of rice brain oil. Journal of the American Oil Chemists’ Society , 83 :315–321. https://doi.org/10.1007/s11746-006-1206-y
  36. Vetter, W., Müller, M., Sommer, K., Schröder, M., & Hammann, S. (2019). Development of equivalent chain length (ECL) rules for lipid compounds. Journal of Chromatography A , 1599 :187–95. https://doi.org/10.1016/j.chroma.2019.04.042
  37. Vetter, W., Schröder, M., & Lehnert, K. (2012). Differentiation of refined and virgin edible oils by means of the trans - andcis -phytol isomer distribution. Journal of Agricultural and Food Chemistry , 60:6103−6107. https://doi.org/10.1021/jf301373k
  38. Yamamoto, Y., Maita, N., Fujisawa, A., Takashima, J., Ishii, Y., & Dunlap, W. C. A. (1999). New vitamin E (α-tocomonoenol) from eggs of the Pacific salmon Oncorhynchus keta . Journal of Natural Products , 62 :1685–1687. https://doi.org/10.1021/np990230v