Control group (n=24)
Mild/moderate group (n=24) Severe group (n=8)
P value
Age, years 44.20 \(\pm\) 5.23 50.70 \(\pm\) 16.05 63.50 \(\pm\) 18.37 0.022
Gender, male 13.0 (54.2) 18.0 (75.0) 6.0 (75.0) 0.265
TGF-\(\mathbf{\beta}\), ng/mL 5.40 \(\pm\) 0.17 5.54 \(\pm\) 0.75 6.32 \(\pm\) 1.39 0.302
Periostin, ng/ml 4.00 \(\pm\) 1.99 5.92 \(\pm\) 2.59 7.55 \(\pm\) 2.66 0.002
C-reactive protein, mg/L 3.16 \(\pm\) 0.20 36.04 \(\pm\ \) 11.67 48.48 \(\pm\) 41.77 0.006
Procalcitonin, ng/ml 0.08 \(\pm\) 0.11 0.09 \(\pm\) 0.17 0.24 \(\pm\) 0.06 <0.001
Fibrinogen, mg/mL 225.66 \(\pm\) 30.83 433.33 \(\pm\) 211.35 416.37 \(\pm\) 164.03 <0.001
D-dimer, \(\mathbf{\mu}\)g/mL 108.75 \(\pm\) 17.87 731.20 \(\pm\) 513.94 1189.25 \(\pm\) 1385.07 <0.001
Ferritin, ng/mL 33.55 \(\pm\) 22.20 258.91 \(\pm\) 152.63 557.12 \(\pm\) 380.14 <0.001
Lactate dehydrogenase (LDH), U/L 138.62 \(\pm\) 19.76 336.00 \(\pm\) 157.46 325.70 \(\pm\) 142.25 <0.001
Creatine kinase (CK), U/L 70.91 \(\pm\) 19.63 97.58 \(\pm\) 84.82 128.25 \(\pm\) 77.47 0.078
Eosinophil count, x103/mm3 0.22 \(\pm\) 0.24 0.06 \(\pm\) 0.08 0.04 \(\pm\) 0.05 0.004
Lymphocyte count, x103/mm3 2.17 \(\pm\) 0.47 1.66 \(\pm\) 0.71 0.87 \(\pm\) 0.46 <0.001