Study Population
Data were extracted for all eligible patients. Inclusion criteria included patients less than 1 year of age who received sirolimus treatment primarily for the management of chylous effusion and required chest tube for the management of effusion due to respiratory distress. Patients of both genders and all races/ethnicities were included. Patients were excluded from the study if they did not have a chest tube at the time of treatment initiation with sirolimus, or had incomplete documentation of chest tube output after sirolimus was started.