Acknowledgements
The MD simulations were partially performed using the computational
resources of Cygnus provided by the Multidisciplinary Cooperative
Research Program (project code: LSC) at the Center for Computational
Sciences (CCS), University of Tsukuba, Japan. This work was supported in
part by the Japan Agency for Medical Research and Development (AMED)
(Grant No. JP20ae0101047h0001), the Japan Agency for Science and
Technology (JST) CREST program (Grant No. JPMJCR20B3), and a
grant-in-aid for innovative research in “Hydrogeomics” and “Biometal
Sciences” (Grant Nos. 19H05047 and 20H05497) by the Ministry of
Education, Culture, Sports, Science and Technology (MEXT), Japan.