Data sources and search strategy
The electronic databases of Pubmed, Embase, Cochrane library, and
ClinicalTrails.gov were searched to identify all eligible studies from
inception to May 5th, 2020; the search strategy of terms mainly included
three parts: atrial fibrillation; anticoagulants or antithrombins or
factor Xa inhibitors or dabigatran or DOAC or NOAC or warfarin or
vitamin K antagonist*; dementia or Alzheimer disease or cognition
disorders or cognitive dysfunction; and their entry terms in MeSH were
also used. Reference lists of all included articles and previous
meta-analysis articles were manually scanned to supplement the
potentially eligible studies. There were no language restrictions. Two
authors (Mingjie Lin and Wenqiang Han) independently searched databases
and the disagreements were checked by themselves. Full search strategies
for all databases are presented in Supplementary Table 1.