*P<0.05 vs normal weight; °P<0.05 vs overweight
RESULTS
A total of 185 OSA subjects (19 normal weight, 57 overweight, 109,
obese) entered the study. Anthropometric data and sleep study from
normal weight, overweight and obese subjects are depicted in Table1.
AHI values were higher in obese (43.3±1.3) than in lean (34.8±3.1) and
overweight subjects (35.5±1.8, P<0.01 ANOVA). Overall, a
direct relationship was evident between AHI and BMI (Figure1). Smokers
were higher in obese group (p<0.05); Systemic Hypertension was
statistically more significant among obese than in leans and overweight
patients (p<0.005). Type 2 diabetes was more represented among
obese patients (p<0.05). Blood total and HDL cholesterol were,
respectively, statistically significant higher and lower in obese
patients (p<0.00001; p<0.0001).
The cardiovascular risk was strictly related to the obesity
(p<0.00002), while the Epworth Questionnaire score and the
Charlson Co-morbidity Index were respectively statistically higher in
the group of obese individuals (p=0.006, p=0.00002) than in the other 2
Groups.
In the whole population, the percentage cardiovascular risk was weakly
related with BMI (r=0.33; P<0.001), but not with AHI.
Figure 1 shows the percentage of cardiovascular risk in the whole
population which was weakly related with BMI (r=0.33;
P<0.001), but not with AHI.