3.2 | Quality of the included studies
We used QUADAS-2 criteria to evaluate each of the included studies in 4 domains: patient selection, index test, reference standard, and test timing. For the included studies, “Patient Selection” and “Flow and Timing” revealed slight shortcomings (13.3% and 33.3%, respectively), which may indicate bias regarding inclusion. Overall, the study quality was satisfactory (Supplementary Figure 1 ).