Associations between endotypes and responses to surgical and
medical treatments
Few studies have been performed evaluating the efficacy of specific
treatments for CRS as a function of endotype. Outcome studies for CRS
have generally not evaluated endotype prior to intervention, relying on
phenotype to subdivide patients. Further, the definition of treatment
success and the time point of evaluation post intervention have also
been variable. Despite these limitations, some tentative statements can
be made based on the presumed endotype of the population treated.