Introduction
Lentigines are brown macules which develop due to increased proliferation of melanocytes at the dermo-epidermal junction. They commonly occur in healthy people but can also be seen in genodermatoses such as Noonan syndrome with multiple lentigines. Eruptive lentigines have previously been described in the context of inflammatory dermatoses, 1 phototherapy, 2 and immunomodulatory therapy. 3 Acral eruptive lentigines have been described following chemotherapy 4 or as a paraneoplastic phenomenon. 5 We report three cases of acral lentiginosis in children following chemotherapy for acute lymphoblastic leukaemia (ALL) which have persisted following cessation of chemotherapy, despite avid photoprotection. All patients remain in remission from ALL.