Statistical analysis for factors associated with transmission and correlation between immune parameters
Associations between household members being positive to SARS-CoV-2 detected by NPS with demographic characteristics, clinical parameters and preventive measures were assessed using generalising estimating equations (assuming an exchangeable correlation structure and distribution of dependent variable as binomial) controlling for the number of contacts within a household (Figure 2 A). The correlation between immune parameters were assessed using tetrachoric correlation as the immune parameters are dichotomous (Figure 2 B).