Prognostic Significance of Monocyte to High-density Lipoprotein Ratio in Patients With Coronary Chronic Total Occlusion
Objective: Monocyte to high-density lipoprotein ratio is a marker of inflammatory response. We investigate the relationship between MHR and mortality in CTO patients.
Methods: Study included 493 patients followed over a period of 73 months. Blood samples taken from patient before coronary angiography.
Results: Median follow-up was 48 months. Patients were divided into two groups: (I) MHR <17.68 (n=278) and (II) MHR ≥17.68 (n=215). Mortality was significantly higher in group II than in group I (n=70 vs. n=43; p<0,001). MHR was found to be an predictor of mortality (OR: 1.089, 95% [CI]: 1.055-1.124, p<0,001). Kaplan-Meier showed lower survival rates in group II than in group I (75.223±2.670 vs. 89.220±2.102, p<0,001).
Conclusion: MHR could be used as a biomarker of mortality in CTO patients
Key words: Chronic total occlusion, risk predictor, monocyte to high-density lipoprotein ratio, long-term mortality, inflammation