Figure legend.
Figure 1.Histopathological findings and treatment course of our index case. A) From left to right: Wright-Giemsa (WG) stain of peripheral blood showing a classical large granular lymphocyte (100X); WG stain of bone marrow (BM) aspiration showing classical LGL (50X); hematoxilin-eosin stain (20X) of the BM biopsy core with infiltration of small lymphocytes characterized by CD3 (20X) and CD8 (20X) positivity by immunostaining. Flow cytometry confirmed the aberrant T-LGL phenotype: CD2, CD3, CD5 dim, CD8, CD16, and CD57. Yellow arrows indicate large granular lymphocytes. B) Timeline depicting the type of treatment received along with duration of administration. On the bottom details on treatments doses.
MTX: Methotrexate, CsA: Cyclosporine, BMBx: Bone marrow biopsy