Figure 2. The levels of Th-related cytokines in plasma of RA patients and its correlation with DAS28 and miR-143-3p.
(A-D) The levels of IFN-γ, IL-4, IL-10 and IL-17A in plasma of moderate patients (n=13) and severe patients (n=18) were detected by ELISA. Data were expressed as the mean ± SEM. * p < 0.05, **p < 0.01, by one-way ANOVA with Dunnett’s post-hoc test.
(E-H) The correlation between IFN-γ, IL-4 (n=31, r=-0.3863, P=0.0159), IL-10 (n=31, r=-0.3256, P=0.0369), IL-17A and DAS28 levels.
(I-L) The correlation between miR-143-3p expression and IFN-γ, IL-4 (n=31, r=0.3239, P=0.0377), IL-10 (n=31, r=0.3443, P=0.0290), IL-17A. The Pearson correlation coefficient was determined.