Case 1
The newborn, male, was admitted with ”scalp defect found after birth”,
mother, 37 years old, father, 40 years old, G3P2, 39 weeks + 1 day of
gestation, born by cesarean section due to ”scarred uterus”, birth
weight 4210g, Apgar score of 9-9-9, clear amniotic fluid, 600 ml of
amniotic fluid, one turn of the umbilical cord around the neck, and no
abnormality of the placenta. After birth, a 3*2.5 cm scalp skin defect
was found on the top of the head, and the skull was visible without bony
defects, and the diagnosis was Aplasia cutis congenital. Ultrasound in
early pregnancy and systemic ultrasound in mid-pregnancy showed no
abnormalities, and Down’s syndrome screening in early and mid-pregnancy
showed no abnormalities.Amniocentesis was recommended for ”advanced
maternal age” and the karyotype and chromosome microarray of the
amniotic fluid showed no abnormalities. There was no previous history of
a similar disease in the child’s family, and the child’s mother had no
history of specific drug exposure during pregnancy. After being informed
of the condition, an emergency debridement and suture combined with
local flap transfer was performed under general anesthesia with tracheal
intubation. The operation was successful, and postoperative ceftizoxime
sodium was used for anti-infective treatment, and wound dressing was
changed. The wound was discharged on the 7th postoperative day, and the
stitches were removed two weeks after surgery, and the wound healed well
on the postoperative review one month later. On review three months
after surgery, the child had no hair follicle growth at the original
skin defect on the top of the head and was growing well. (Figure 1)